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NAD+

Price range: $100.00 through $145.00

SKU: YPB.223 Categories: ,

Description

A single-component research material supplied for controlled research environments. Suitable for studies involving nucleotide cofactor characterization and method development in model systems.


Composition

• NAD+
Format: Synthetic
Fill Volume: 6 mL vial
Appearance: Sterile solution in a sealed research vial


Research Focus (non-clinical)

• Identity and purity assessment via HPLC/LC-MS and UV-Vis quantitation
• Assay development and calibration for enzymatic cycling or cell-free systems
• Chromatographic method optimization for impurity/degradation profiling (e.g., NADH/NADP)
• Stability characterization under laboratory storage conditions (temperature, pH, light)

For qualified research professionals and institutional laboratories. Not for human use.


Documentation & Quality Assurance

Each lot is sourced through our verified global supply chain with emphasis on traceability and quality control. We work diligently to obtain and maintain third-party analytical reports (HPLC/LC-MS) and Certificates of Analysis for each batch, as part of our ongoing quality process. These documents are reviewed internally and displayed as they become available. Independent third-party testing is also performed on select lots to confirm identity, purity, and alignment with our internal specifications.


Important Notice

This product is intended for laboratory research use only. It is not intended for human or veterinary use, and must not be used for diagnostic, therapeutic, or clinical purposes.
This material is not a drug, medical device, or dietary supplement, and has not been evaluated by the U.S. Food and Drug Administration.


Quality & Manufacturing

All materials are sourced from carefully vetted domestic and international manufacturing partners who follow quality systems consistent with ISO and cGMP principles. Each supplier is reviewed for reliability, documentation integrity, and transparency in testing.

We require a verified purity of 99% or higher and perform independent third-party spot testing to confirm that select lots meet our internal standards for identity, purity, and composition. Where available, endotoxin testing results are included on Certificates of Analysis to verify laboratory purity; their inclusion is for research quality assessment only and does not imply suitability for human or veterinary use.

All research materials are sealed for integrity and packaged for stability during storage and transport from manufacturing through final delivery.

Additional information

Weight 0.2 lbs
Dosage

500mg, 1000mg

Storage Instructions

All our research peptides are manufactured using a lyophilization (freeze-drying) process. This method is designed to maintain product integrity and allows vials to remain stable during shipping for approximately 3–4 months.

Once a vial is reconstituted with bacteriostatic water, it should be stored in the refrigerator to help maintain stability. Under these conditions, reconstituted material is generally considered stable for up to 30 days.

Lyophilization is a dehydration technique in which compounds are frozen and then exposed to low pressure. This causes the water in the vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure. This powder can be kept at room temperature until reconstitution.

Upon receipt, products should be stored away from heat and light. For short-term use, refrigeration at approximately 4°C (39°F) is suitable. For long-term storage (several months to years), vials may be placed in a freezer at approximately -80°C (-112°F). Freezing is the preferred method for preserving product stability over extended periods.

⚠️ Important Notice: These products are intended for research use only. Not for human consumption.

Certificate of Analysis

Every batch undergoes rigorous third-party laboratory testing to verify identity, purity (≥98%), and quality before release.

Select a product option above to view its Certificate of Analysis.

All Available COAs

Third-Party Verified ≥98% Purity HPLC & MS Tested

Research Use Only

These studies reference research-grade peptides for laboratory and scientific investigation only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.

Published Scientific Research

Peer-reviewed laboratory research investigating research peptides from leading scientific databases

Molecular Analysis
PubMed

REV-ERBα regulates brain NAD levels and tauopathy via an NFIL3-CD38 axis.

Nature aging 2025

However, the molecular mechanisms of brain NAD regulation are incompletely understood. In cardiac tissue, the circadian nuclear receptor REV-ERBα has been shown to regulate NAD via control of the NAD-producing enzyme NAMPT.

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Molecular Analysis
PubMed

Vascular Endothelial NAMPT-Mediated NAD Biosynthesis Regulates Angiogenesis and Cardiometabolic Functions in Male Mice.

Aging cell 2025

Aging is associated with metabolic dysfunction and cardiovascular abnormalities. However, the precise molecular mechanisms linking aging-associated NAD deficiency to cardiometabolic dysfunction remain unclear.

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In Vitro Study
PubMed

Phase separation of FSP1 promotes ferroptosis.

Nature 2023

icFSP1-induced FSP1 condensates show droplet-like properties consistent with phase separation, an emerging and widespread mechanism to modulate biological activity.

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Molecular Analysis
PubMed

NAD metabolism modulates inflammation and mitochondria function in diabetic kidney disease.

The Journal of biological chemistry 2023

Inflammation is closely associated with mitochondrial damage. These effects were associated with decreased inflammation, at least in part via inhibiting the activation of the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) signaling pathway.

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Molecular Analysis
PubMed

NAMPT-dependent NAD biosynthesis controls circadian metabolism in a tissue-specific manner.

Proceedings of the National Academy of Sciences of the United States of America 2023

NAMPT coordinates the rhythmicity of TCA cycle intermediates in BAT, but not in WAT, and loss of NAD abolishes these oscillations similarly to high-fat diet-induced circadian disruption.

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Molecular Analysis
PubMed

Inhibition of NAD+-Dependent Metabolic Processes Induces Cellular Necrosis and Tumor Regression in Rhabdomyosarcoma Models.

Clinical cancer research : an official journal of the American Association for Cancer Research 2023

One such target is nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in the NAD+ salvage pathway. We used orthotopic xenograft models to examine tolerability, efficacy, and drug mechanism in vivo.

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